What if I can’t swallow mifepristone? Can I crush it?

Posted April 22, 2026

Yes! If you have trouble swallowing pills, you can split the tablet in half or crush the mifepristone and swallow it with water or juice.

It will still be just as effective. What matters is that you take the full dose.


How do I take mifepristone if I crush it?

There are a few ways to crush the pill — but you don’t need anything fancy.

  • You can use a pill crusher from a pharmacy
  • A mortar and pestle works too
  • Or place the pill between two spoons or inside folded paper (wax paper works best), then press down with a heavy object

Once it’s crushed into a powder:

  • Mix it with a small amount of food (like apple sauce or pudding), water or juice
  • Swallow all of the pieces it right away

A small amount of food or drink can help with the taste — mifepristone can be a little bitter and chalky, which is totally normal. Mifepristone should still be swallowed, even when crushed.

This is different from the second set of pills, misoprostol, which are usually held in your cheeks or under your tongue. The misoprostol tablets should not be split in half or crushed.


What if I throw up after taking mifepristone?

If mifepristone stays in your body for at least 60 minutes, you’ve absorbed most of the medication and do not need another dose. But if you throw up before 60 minutes or see the pill residue when you vomit, you’ll need to take more Mifepristone. Keep in mind, it may take time to request more mifepristone from the provider.

Learn more about what to do if you throw up and remedies for nausea.

Another option is switching to the misoprostol only protocol (which requires more misoprostol).

Important: Mifepristone by itself will not end a pregnancy—it must be taken with misoprostol. But, people still successfully and safely have an abortion using only misoprostol, it just requires more of the tablets.

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